====== Search analogs for multiple hits (one hit at a time) ======

If your hits are from fairly different scaffolds, it might make more sense to run separate similarity searches on each of them, merge the results into a single compound collection, and request a quote for the merged collection.

  - Go to **[[https://mcule.com/search/|"FIND CHEMICALS / SINGLE QUERY"]]**
  - Specify your first query (either by drawing or by providing a chemical identifier such as mcule ID, SMILES, InChI or InChIKey)
  - If you want to keep a particular substructure in all resulting analogs, modify your query accordingly (delete unnecessary parts) and select **"Substructure"** search type. Note: you can block substituents at particular positions of the molecule by placing explicit hydrogen atoms.
  - If you simply want the overall most similar analogs of your compound, select **"Similarity"** search type
  - Click on **"SEARCH"**
  - Repeat steps 1-5 for all your hits
  - Go to **[[https://mcule.com/collection/|"COLLECTIONS"]]**
  - You can select your most recent collections (results of your analog searches) and click on **"MERGE"** to merge them into a single collection
  - Alternatively, you can open your most recent collections one by one, select the most interesting compounds and click on the **"ADD TO"** button to add them to a new or an already existing collection
  - Go to the final collection that contains the selected analogs you would like to order and click on the orange **"QUOTE"** button in the top right corner
  - Fill out the quote form
  - Click on either **"INSTANT QUOTE"** (quote will be generated on-the-fly - **[[https://mcule.com/pricing/|subscription required]]**) or **"NEXT-DAY QUOTE"** (we will send you a quote by e-mail in 24-48 hours)

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