====== Search close analogs for a single hit ====== If you have a single hit and want to search and order its close analogs, follow these steps: - Go to **[[https://mcule.com/search/|"FIND CHEMICALS / SINGLE QUERY"]]** - Specify your query (either by drawing or by providing a chemical identifier such as mcule ID, SMILES, InChI or InChIKey) - If you want to keep a particular substructure in all resulting analogs, modify your query accordingly (delete unnecessary parts) and select **"Substructure"** search type. Note: you can block substituents at particular positions of the molecule by placing explicit hydrogen atoms. - If you simply want the overall most similar analogs of your compound, select **"Similarity"** search type - Click on **"SEARCH"** - After the search was finished and the most similar compounds were displayed, click on the orange **"QUOTE"** button in the top right corner - Fill out the quote form - Click on either **"INSTANT QUOTE"** (quote will be generated on-the-fly - **[[https://mcule.com/pricing/|subscription required]]**) or **"NEXT-DAY QUOTE"** (we will send you a quote by e-mail in 24-48 hours) **__[[usecases|Go back to use cases >>]]__**