Here is the list of open source and commercial tools we are using for developing mcule.com:

• InChI - our Structure Registration System is based on InChI. We are the member of InChI Trust organization.
• OpenBabel - 2D, 3D structure, property and fingerprint generation.
• Indigo - Fingerprint generation and substructure searching, chemical format conversions.
• Chem-fingerprint - Fast calculation of Tanimoto coefficient.
• sc-PDB - ~10,000 PDB structures prepared for docking (scientific paper can be accessed here)
• GLmol - 3D molecular viewer using WebGL and Javascript

• MChem - our in-house tool. It implements the various structure checks and normalization steps of our Structure Registration System
• ChemWriter and ChemVector developed by Metamolecular - Various improvements and customization have been requested and sponsored by mcule.com.

• Python - Our favorite programming language
• Django - High-level Python Web framework

• Mercurial - Free, distributed source control management tool
• Bitbucket - A free code DVCS hosting site for Git and Mercurial

• jQuery - A fast, concise, cross-browser JavaScript Library
• CoffeeScript - A language that compiles into JavaScript.
• Sass - An extension of CSS3, adding nested rules, variables, mixins, selector inheritance, and more.
• Compass - An open-source CSS Authoring Framework. It uses Sass.

• virtualenv - A tool to create isolated Python environments.
• virtualenvwrapper - A set of extensions to virtualenv.
• pip - A tool for installing and managing Python packages.

• Amazon Web Services
• Softlayer - Cloud and dedicated servers

• PostgreSQL - A powerful, open source object-relational database system.
• Redis - An open source, advanced key-value store.

• Fabric - A Python library and command-line tool for streamlining the use of SSH for application deployment or systems administration tasks.

• Nginx - An HTTP and reverse proxy server.
• Gunicorn - A Python WSGI HTTP Server for UNIX.
• Supervisor - A system to monitor and control a number of processes on UNIX-like operating systems.

• Celery - Distributed Task Queue

• Munin - Munin is a networked resource monitoring tool.