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applications [2014/01/16 18:40] flackapplications [2024/04/09 08:35] (current) rkiss
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 **[[1clickdocking|Learn more »]]** **[[1clickdocking|Learn more »]]**
-===== 1-CLICK SCAFFOLD HOP ===== 
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-Scaffold hopping is about finding novel active ligands structurally different from a reference ligand (Query). Scaffold hopping can be particularly useful during lead optimization, when certain parts of lead molecules need to be replaced to fix IP, toxicity, selectivity or pharmacokinetic issues. 1-Click Scaffold Hop utilizes the powerful FTrees Visual Similarities algorithm (link), which can identify structurally different scaffolds that are still active. 
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-**[[1clickscaffoldhop|Learn more »]]** 
 ===== PROPERTY CALCULATOR ===== ===== PROPERTY CALCULATOR =====
  
applications.1389897650.txt.gz · Last modified: 2014/01/16 18:40 by flack