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usecase1csh [2013/10/10 16:09] flackusecase1csh [2013/12/02 22:26] – link to 1-click scaffold hop's page sanmark
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 ====== Generate new ideas and eliminate problematic parts by 1-Click Scaffold Hop ====== ====== Generate new ideas and eliminate problematic parts by 1-Click Scaffold Hop ======
  
-Scaffold hopping is about finding novel active ligands structurally different from a reference ligand (query). Scaffold hopping can be particularly useful during lead optimization to generate new ideas or to eliminate particular parts of your hit/lead to fix IP, toxicity, selectivity or pharmacokinetic issues. 1-Click Scaffold Hop is searching different subsets of **[[purchasable|Purchasable compounds]]** +Scaffold hopping is about finding novel active ligands structurally different from a reference ligand (query). Scaffold hopping can be particularly useful during lead optimization to generate new ideas or to eliminate particular parts of your hit/lead to fix IP, toxicity, selectivity or pharmacokinetic issues. [[1clickscaffoldhop|1-Click Scaffold Hop]] is searching different subsets of **[[purchasable|Purchasable compounds]]** 
 that might be structurally different but share pharmacophore properties with those of the query. that might be structurally different but share pharmacophore properties with those of the query.
  
usecase1csh.txt · Last modified: 2013/12/02 22:28 by sanmark